The Impact of First- And Second-Generation Antiepileptic Drugs on Internal Organs: A Comprehensive Review
Keywords:
Antiepileptic drugs, first-generation AEDs, second-generation AEDs, hepatotoxicity, nephrotoxicity, cardiovascular effectsAbstract
Antiepileptic drugs (AEDs) are essential in the management of epilepsy and other neurological disorders. However, their impact on internal organs is a growing concern, particularly with prolonged use. This review article explores the effects of first- and second-generation AEDs on various internal organs, including the liver, kidneys, heart, and gastrointestinal system. The article synthesizes current research to provide a comprehensive understanding of the potential risks associated with these medications, highlighting the need for careful monitoring and individualized treatment strategies.












